From Geneva: Head towards Lausanne on the A1 motorway.  Take the Lausanne interchange and follow the A9 direction Simplon-Grand St-Bernard.  Exit at Montreux, go down to the lake and turn left.  Le Montreux Palace is about 500 meters up this road.
    
From Lausanne:
Take the A9 motorway in the direction of Simplon-Grand St-Bernard, exit at Montreux, go down to the lake and turn left.  Le Montreux Palace is about 500 meters up this road.
  
From Zurich:
A1 motorway in the direction of Bern-Basel-Dietikon to the Geneva-Lausanne-Neuchâtel sign, motorway A12, interchange direction Vevey, motorway A9, Montreux exit, go down to the lake and turn left.  Le Montreux Palace is about 500 meters up this road.