From Nice and its airport follow the signs to Cannes, either taking the motor way A8 or the “Bord de Mer” coastal road to Cagnes-sur-Mer. Once there take the road to Grasse and as soon as you see indications to La Colle-sur-Loup and St. Paul, follow them until you find the hotel signs (Mas d’Artigny is between La Colle and St. Paul).
From Cannes follow the signs to Nice either on A8, the RN 7 road or the Bord de Mer road, until you reach Cagnes-sur-Mer. Then proceed as above.