From Florence:
Take Motorway A1 South towards Rome to the Val di Chiana exit. From
there take the state highway SS 327 and then the SS 75bis to Perugia (it
will take another 25 minutes to reach Spello) and continue towards
Assisi-Foligno to the Spello exit.
From Rome:
Take Motorway A1 North towards Florence to the Orte exit. From there
take the state highway SS 204 to the junction with the E45; at this
point follow this route towards Todi-Perugia, then continue towards
Assisi-Foligno to the Spello exit.
Once in Spello, look for the old part of the town (up hill) and the
hotel is located on the left hand side of the main street that goes up
town.