From Florence:

Take Motorway A1 and head South-East direction Roma. Take Monte San Savino exit through the toll booth and turn right at the stop sign, direction Castiglion Fiorentino. Continue along this road through Badicorte and turn left at the next stop sign. Follow signs for Castiglion Fiorentino, keep straight through the next stop sign and continue along this road, passing through Manciano, for about 8 Kms. You will arrive at a Castiglion Fiorentino sign, continue over the bridge and turn right at the next intersection. Follow the road around the curve, the train lines should be on your right, and turn right at the first set of traffice lights. Keep straight through the second set of traffic lights and turn left at the third set. Continue along this road following the signs for Citta di Castello. For Palazzo Terranova from here turn right and follow the windy road for about 24 Kms., passing through Santa Cristina, Volterrano and Morra to arrive in Ronti. Ronti is very small so keep your eyes open!!! Slow down when you see the sign indicating that you have arrived in Ronti. On your right look for the clump of Cypress trees at the entrance to the Cemetery.  Take the small road to the left just before you get to the Cypress trees. At the end of this road turn left and then take the next right at the large tree. You are now on a dirt road which you follow for 2 Kms. It is steep and bumpy in parts but keep going. You will catch a glimpse of the Palazzo through the trees.

From Rome:

Head north towards the ring road (tangenziale) and follow signs to Motorway A1 direction to Firenze. Take exit 9-10 for Firenze and continue in the direction for Orte. Take exit at Orte and get onto the E45 , direction Perugia and Cesena. Continue along the E45 and take the exit to Promano. Follow directions for Citta di Castello, passing through Cinquemiglia. From here on follow directions from Citta de Castello explained in directions from Florence.