From the airport:
Take Highway 80 to Cristoforo Colombo Way and follow the directions to city center/San Giovanni. Go to Termini RR station and then Via Veneto.

From Aquila/Bari (East)

Take Highway A24 and follow to Tangenziale Est. The take Via Tiburtina and follow the directions to Termini RR railway station and then to Via Veneto.

From Florence (North)

From Highway A1, take the Roma Est Exit and follow the directions to Tangenziale Est. Then take Via Tiburtina to Termini RR Station and continue to Via Veneto.

From Naples (South)
From Highway A1, take the Roma Est Exit and follow directions to Tangenziale Est. Then take Via Tiburtina to Termini RR Station and continue to Via Veneto.